NEFA minimal model parameters estimated from the oral glucose tolerance test and the meal tolerance test

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NEFA minimal model parameters estimated from the oral glucose tolerance test and the meal tolerance test.

The kinetics of nonesterified fatty acid (NEFA) metabolism in humans requires quantification to facilitate understanding of diseases like type 1 and 2 diabetes, metabolic syndrome, and obesity, and the mechanisms underpinning various interventions. Oral glucose tolerance tests (OGTT) and glucose meal tolerance tests (MTT) are potentially useful procedures for enabling quantification of NEFA kin...

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Reproducibility of the oral glucose tolerance test and the rice-meal test in mild diabetics.

Reproducibility of 100 gm. oral glucose tolerance test and of Sakaguchi's rice-meal test were studied in sixty untreated mild diabetic patients with fasting blood sugar below 140 mg. per 100 ml. (Hagedorn-Jensen method). The tests were performed twice within a one-week interval. There were considerable variations of blood sugar levels in the same individuals between the duplicate tests. Variati...

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The One-Hour Oral Glucose Tolerance Test

Response of middle-aged men to loo-gram and 50-gram doses of glucose given fasting and 1, 2, and 3 hours after meal. PREFACE This is one of several studies designed to evaluate examination procedures used in the first cycle of the Health ESamination Survey. These studies constitute efforts to define and to measure some of the components of variation in the examination techniques. Where the tech...

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The oral glucose tolerance test, revisited.

Hyperglycaemia is necessary for the diagnosis of diabetes. For more than 35 years there has been a spirited controversy about the diagnostic criteria for Type 2 diabetes, in particular about the oral glucose tolerance test (OGTT). In a 1975 paper Marvin Siperstein referred to the OGTT as ‘a pitfall in the diagnosis of diabetes mellitus’. Now the controversy has returned in the wake of the 1997 ...

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Lessons From the Mixed-Meal Tolerance Test

OBJECTIVE Mixed-meal tolerance test (MMTT) area under the curve C-peptide (AUC CP) is the gold-standard measure of endogenous insulin secretion in type 1 diabetes but is intensive and invasive to perform. The 90-min MMTT-stimulated CP ≥0.2 nmol/L (90CP) is related to improved clinical outcomes, and CP ≥0.1 nmol/L is the equivalent fasting measure (FCP). We assessed whether 90CP or FCP are alter...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

سال: 2008

ISSN: 0363-6119,1522-1490

DOI: 10.1152/ajpregu.90317.2008